| pubmed-article:12360232 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12360232 | lifeskim:mentions | umls-concept:C0024660 | lld:lifeskim |
| pubmed-article:12360232 | lifeskim:mentions | umls-concept:C1099354 | lld:lifeskim |
| pubmed-article:12360232 | lifeskim:mentions | umls-concept:C0598496 | lld:lifeskim |
| pubmed-article:12360232 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:12360232 | pubmed:dateCreated | 2002-10-2 | lld:pubmed |
| pubmed-article:12360232 | pubmed:abstractText | Among the 3 billion base pairs of the human genome, there are approximately 30,000-40,000 protein-coding genes, but the function of at least half of them remains unknown. A new tool - short interfering RNAs (siRNAs) - has now been developed for systematically deciphering the functions and interactions of these thousands of genes. siRNAs are an intermediate of RNA interference, the process by which double-stranded RNA silences homologous genes. Although the use of siRNAs to silence genes in vertebrate cells was only reported a year ago, the emerging literature indicates that most vertebrate genes can be studied with this technology. | lld:pubmed |
| pubmed-article:12360232 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12360232 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12360232 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12360232 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12360232 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12360232 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12360232 | pubmed:issn | 1471-0056 | lld:pubmed |
| pubmed-article:12360232 | pubmed:author | pubmed-author:SharpPhillip... | lld:pubmed |
| pubmed-article:12360232 | pubmed:author | pubmed-author:McManusMichae... | lld:pubmed |
| pubmed-article:12360232 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12360232 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:12360232 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12360232 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12360232 | pubmed:pagination | 737-47 | lld:pubmed |
| pubmed-article:12360232 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:meshHeading | pubmed-meshheading:12360232... | lld:pubmed |
| pubmed-article:12360232 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12360232 | pubmed:articleTitle | Gene silencing in mammals by small interfering RNAs. | lld:pubmed |
| pubmed-article:12360232 | pubmed:affiliation | Center for Cancer Research, Massachusetts Institute of Technology, 40 Ames Street E17-526, Cambridge, Massachusetts 02139, USA. mmcmanus@mit.edu | lld:pubmed |
| pubmed-article:12360232 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12360232 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12360232 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:12360232 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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