| pubmed-article:12357368 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12357368 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:12357368 | lifeskim:mentions | umls-concept:C0079772 | lld:lifeskim |
| pubmed-article:12357368 | lifeskim:mentions | umls-concept:C0149678 | lld:lifeskim |
| pubmed-article:12357368 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:12357368 | lifeskim:mentions | umls-concept:C0449560 | lld:lifeskim |
| pubmed-article:12357368 | lifeskim:mentions | umls-concept:C0699759 | lld:lifeskim |
| pubmed-article:12357368 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:12357368 | pubmed:dateCreated | 2002-10-1 | lld:pubmed |
| pubmed-article:12357368 | pubmed:abstractText | We studied eight patients with characteristic features of angio-immunoblastic T cell lymphoma (AILD-TL) associated with more than 25% of large B cells. Polymerase chain reaction (PCR) analysis showed a clonal rearrangement of the T cell receptor (TCR)-gamma chain gene in all cases. One additional case showed a clonal rearrangement of the TCR-beta chain gene by Southern blot hybridization. PCR analysis showed a clonal immunoglobulin rearrangement in three cases presenting with more than 50% of large B cells whereas the other cases had a germline configuration. In 6/8 cases, double-labeling immunohistochemistry and in situ hybridization demonstrated that Epstein-Barr virus (EBV) was mostly present in the large B cells but also detected in some T cells. We further evaluated the frequency of AILD-TL with more than 25% of large B cells in the 106 cases collected by the French GELA group and found an incidence of 18%. The outcome of these patients did not differ significantly from those with less than 25% of B cells. With this approach we confirm the heterogeneity of AILD-TL features and the possible association with a substantial numbers of CD20(+), EBV(+) large B cells. We propose to denominate these cases as 'AILD-TL rich in large B cells' and to consider them as a different entity which can be misdiagnosed as a reactive process or as T cell rich B cell lymphoma. | lld:pubmed |
| pubmed-article:12357368 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12357368 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12357368 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12357368 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12357368 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12357368 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12357368 | pubmed:issn | 0887-6924 | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:BrousseNN | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:GaulardPP | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:MacintyreEE | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:HermineOO | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:CanioniDD | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:DelabesseEE | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:DamotteDD | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:Lome-Maldonad... | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:RaffouxEE | lld:pubmed |
| pubmed-article:12357368 | pubmed:author | pubmed-author:French... | lld:pubmed |
| pubmed-article:12357368 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12357368 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:12357368 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12357368 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12357368 | pubmed:pagination | 2134-41 | lld:pubmed |
| pubmed-article:12357368 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:meshHeading | pubmed-meshheading:12357368... | lld:pubmed |
| pubmed-article:12357368 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12357368 | pubmed:articleTitle | Angio-immunoblastic T cell lymphoma (AILD-TL) rich in large B cells and associated with Epstein-Barr virus infection. A different subtype of AILD-TL? | lld:pubmed |
| pubmed-article:12357368 | pubmed:affiliation | Department of Pathology (EA 219, University Paris V), Hôpital Necker-Enfants Malades, France. | lld:pubmed |
| pubmed-article:12357368 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12357368 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12357368 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12357368 | lld:pubmed |
