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pubmed-article:12239970pubmed:abstractTextInterleukin-1 beta (IL-1 beta) plays an important role in gastric inflammation and physiology. Functional polymorphisms of IL-1 beta gene have been related to different risks of gastric cancer and duodenal ulcer but their role in gastric ulcer remains unknown. In this study, we investigate a plausible association between gastric ulcer and the polymorphisms in the IL-1 beta and IL-1 receptor antagonist (IL-1RN) genes. The relationships among the cytokine genotyping, other environmental risks such as Helicobacter pylori infection and smoking, and clinical characteristics of gastric ulcer were also determined.lld:pubmed
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pubmed-article:12239970pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:12239970pubmed:articleTitleAssociation of polymorphisms of interleukin-1 beta gene and Helicobacter pylori infection with the risk of gastric ulcer.lld:pubmed
pubmed-article:12239970pubmed:affiliationDepartment of Internal Medicine, National Taiwan University Hospital College of Medicine, National Taiwan University, Taipei, Taiwan.lld:pubmed
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