| pubmed-article:12230940 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0152035 | lld:lifeskim |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0024400 | lld:lifeskim |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0913092 | lld:lifeskim |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0597298 | lld:lifeskim |
| pubmed-article:12230940 | lifeskim:mentions | umls-concept:C0681842 | lld:lifeskim |
| pubmed-article:12230940 | pubmed:issue | 13 | lld:pubmed |
| pubmed-article:12230940 | pubmed:dateCreated | 2002-9-16 | lld:pubmed |
| pubmed-article:12230940 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:abstractText | We report here the gene for DC-SIGN from Chinese rhesus macaques. DC-SIGN is a C-type lectin expressed by dendritic cells (DCs). It is involved in the interaction of DCs with T cells, and in transmission to T cells of HIV-1 and SIV. Alternative splicing in human DC-SIGN yields A and B isoforms of the protein. The overall organization of the rhesus macaque gene is similar to that of the human gene. Translation of B isoforms cannot occur because of a point substitution. The coding sequence shows that we have cloned a fourth allele for rhesus macaque DC-SIGN. This allele shows high homology to the other rhesus macaque alleles. However, at the protein level, the homology is highest with the pigtail macaque protein. This suggests a convergent evolution of DC-SIGN in macaques living in China. The importance of DC-SIGN variability in the immune response remains to be investigated. | lld:pubmed |
| pubmed-article:12230940 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12230940 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12230940 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12230940 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12230940 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:12230940 | pubmed:issn | 0889-2229 | lld:pubmed |
| pubmed-article:12230940 | pubmed:author | pubmed-author:SantosPatríci... | lld:pubmed |
| pubmed-article:12230940 | pubmed:author | pubmed-author:PetitprezKari... | lld:pubmed |
| pubmed-article:12230940 | pubmed:author | pubmed-author:ButorCécileC | lld:pubmed |
| pubmed-article:12230940 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12230940 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:12230940 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:12230940 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12230940 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12230940 | pubmed:pagination | 977-81 | lld:pubmed |
| pubmed-article:12230940 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:meshHeading | pubmed-meshheading:12230940... | lld:pubmed |
| pubmed-article:12230940 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12230940 | pubmed:articleTitle | Gene for chinese rhesus macaque DC-SIGN predicts the existence of A but not B isoforms of the protein. | lld:pubmed |
| pubmed-article:12230940 | pubmed:affiliation | Département d'Immunologie, Institut Cochin, INSERM U567, CNRS UMR8104, Université Paris V-René Descartes, 75014 Paris, France. psantos@mail.cochin.inserm.fr | lld:pubmed |
| pubmed-article:12230940 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12230940 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:574211 | entrezgene:pubmed | pubmed-article:12230940 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12230940 | lld:pubmed |
