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| pubmed-article:12226822 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:12226822 | lifeskim:mentions | umls-concept:C0241664 | lld:lifeskim |
| pubmed-article:12226822 | lifeskim:mentions | umls-concept:C0017431 | lld:lifeskim |
| pubmed-article:12226822 | lifeskim:mentions | umls-concept:C1512456 | lld:lifeskim |
| pubmed-article:12226822 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:12226822 | pubmed:dateCreated | 2002-9-12 | lld:pubmed |
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| pubmed-article:12226822 | pubmed:abstractText | GB virus C or hepatitis G virus (GBV-C/HGV) is highly prevalent among population groups at risk of parenterally transmitted viral agents, but it has also a worldwide distribution in other non-risk population groups. GBV-C/HGV RNA and antibodies against its envelope protein (anti-E2 Abs) were found in 3/86 (3%) and 7/89 (8%) of biomedical science personnel (BSP), in 31/453 (7%) and 37/200 (19%) of blood donors (BD), and in 6/64 (9%) and 26/59 (44%) of hemodialysis patients (HD) from Caracas, Venezuela. A significant gradient of GBV-C/HGV exposure (anti-E2 Abs and/or GBV-C/HGV RNA) was found between BSP (lowest prevalence), BD, and HD (P < 0.001). GBV-C/HGV RNA and anti-E2 Abs were also found in 2/69 (2.9%) and 2/44 (4.5%) of individuals from a rural community, in 9/162 (5.5%) and 2/40 (5%) of West Amerindians, and in 14/56 (25%) and 4/53 (7.5%) of South Amerindians. Socioeconomic and cultural factors may have contributed to the relatively high risk of exposure to GBV-C/HGV in BD and Amerindians. Whereas GBV-C/HGV genotypes 1 (n = 1), 2 (n = 6), and 3 (n = 22) were present in Venezuela, only the Asiatic genotype 3 was found infecting Amerindians and rural populations (n = 16). Genotype assignment based on the 5' noncoding region of the GBV- C/HGV genome was corroborated in some isolates by genetic analysis of the E2 region. This report confirms the circulation of the Asiatic genotype of GBV-C/HGV among Amerindians, suggesting an old origin of GBV-C/HGV. This might be associated with the apparently low pathogenesis of this virus. | lld:pubmed |
| pubmed-article:12226822 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12226822 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12226822 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12226822 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12226822 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12226822 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:12226822 | pubmed:issn | 0146-6615 | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:VillegasLL | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:LópezJosé LJL | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:LiprandiFerdi... | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:LoureiroCarme... | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:AlonsoRoberto... | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:PachecoBelkis... | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:UzcáteguiMarí... | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:LeónGracielaG | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:12226822 | pubmed:author | pubmed-author:PujolFlor HFH | lld:pubmed |
| pubmed-article:12226822 | pubmed:copyrightInfo | Copyright 2002 Wiley-Liss, Inc. | lld:pubmed |
| pubmed-article:12226822 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12226822 | pubmed:volume | 68 | lld:pubmed |
| pubmed-article:12226822 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12226822 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12226822 | pubmed:pagination | 357-62 | lld:pubmed |
| pubmed-article:12226822 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:12226822 | pubmed:meshHeading | pubmed-meshheading:12226822... | lld:pubmed |
| pubmed-article:12226822 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12226822 | pubmed:articleTitle | High prevalence of GB virus C/hepatitis G virus genotype 3 among autochthonous Venezuelan populations. | lld:pubmed |
| pubmed-article:12226822 | pubmed:affiliation | Laboratorio de Biología de Virus, Centro de Microbiología y Biología Celular, IVIC, Caracas, Venezuela. | lld:pubmed |
| pubmed-article:12226822 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12226822 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
