| pubmed-article:12218008 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C0004651 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C0445750 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C1136170 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C0449943 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:12218008 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:12218008 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:12218008 | pubmed:dateCreated | 2002-9-9 | lld:pubmed |
| pubmed-article:12218008 | pubmed:abstractText | The Gifsy-2 temperate bacteriophage of Salmonella enterica serovar Typhimurium contributes significantly to the pathogenicity of strains that carry it as a prophage. Previous studies have shown that Gifsy-2 encodes SodCI, a periplasmic Cu/Zn superoxide dismutase, and at least one additional virulence factor. Gifsy-2 encodes a Salmonella pathogenicity island 2 type III secreted effector protein. Sequence analysis of the Gifsy-2 genome also identifies several open reading frames with homology to those of known virulence genes. However, we found that null mutations in these genes did not individually have a significant effect on the ability of S. enterica serovar Typhimurium to establish a systemic infection in mice. Using deletion analysis, we have identified a gene, gtgE, which is necessary for the full virulence of S. enterica serovar Typhimurium Gifsy-2 lysogens. Together, GtgE and SodCI account for the contribution of Gifsy-2 to S. enterica serovar Typhimurium virulence in the murine model. | lld:pubmed |
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| pubmed-article:12218008 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12218008 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12218008 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12218008 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12218008 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12218008 | pubmed:issn | 0021-9193 | lld:pubmed |
| pubmed-article:12218008 | pubmed:author | pubmed-author:UzzauSergioS | lld:pubmed |
| pubmed-article:12218008 | pubmed:author | pubmed-author:SlauchJames... | lld:pubmed |
| pubmed-article:12218008 | pubmed:author | pubmed-author:HoTheresa DTD | lld:pubmed |
| pubmed-article:12218008 | pubmed:author | pubmed-author:Figueroa-Boss... | lld:pubmed |
| pubmed-article:12218008 | pubmed:author | pubmed-author:WangMinhuaM | lld:pubmed |
| pubmed-article:12218008 | pubmed:author | pubmed-author:BossiLionello... | lld:pubmed |
| pubmed-article:12218008 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12218008 | pubmed:volume | 184 | lld:pubmed |
| pubmed-article:12218008 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12218008 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12218008 | pubmed:pagination | 5234-9 | lld:pubmed |
| pubmed-article:12218008 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:12218008 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12218008 | pubmed:articleTitle | Identification of GtgE, a novel virulence factor encoded on the Gifsy-2 bacteriophage of Salmonella enterica serovar Typhimurium. | lld:pubmed |
| pubmed-article:12218008 | pubmed:affiliation | Department of Microbiology. College of Medicine, University of Illinois, Urbana, Illinois 61801, USA. | lld:pubmed |
| pubmed-article:12218008 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12218008 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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