| pubmed-article:12217374 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C0043047 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C0033262 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C1749467 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C0360363 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:12217374 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:12217374 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:12217374 | pubmed:dateCreated | 2002-9-9 | lld:pubmed |
| pubmed-article:12217374 | pubmed:abstractText | Water soluble N-benzyltriazolium or N-benzylimidazolium salt type prodrugs of several highly lipophilic triazole or imidazole antifungals have been synthesized. They were designed to undergo an enzymatic activation followed by a self-cleavage to release a parent drug. The prodrugs such as 16 had enough chemical stability and water solubility for parenteral use and were rapidly and quantitatively converted to the active substance in human plasma. | lld:pubmed |
| pubmed-article:12217374 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12217374 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12217374 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12217374 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12217374 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:12217374 | pubmed:author | pubmed-author:ShimmaNobuoN | lld:pubmed |
| pubmed-article:12217374 | pubmed:author | pubmed-author:IchiharaShige... | lld:pubmed |
| pubmed-article:12217374 | pubmed:author | pubmed-author:OhwadaJunJ | lld:pubmed |
| pubmed-article:12217374 | pubmed:author | pubmed-author:MurasakiChika... | lld:pubmed |
| pubmed-article:12217374 | pubmed:author | pubmed-author:YamazakiToshi... | lld:pubmed |
| pubmed-article:12217374 | pubmed:author | pubmed-author:UmedaIsaoI | lld:pubmed |
| pubmed-article:12217374 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12217374 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:12217374 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:12217374 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12217374 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12217374 | pubmed:pagination | 2775-80 | lld:pubmed |
| pubmed-article:12217374 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
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| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:meshHeading | pubmed-meshheading:12217374... | lld:pubmed |
| pubmed-article:12217374 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12217374 | pubmed:articleTitle | Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals. | lld:pubmed |
| pubmed-article:12217374 | pubmed:affiliation | Department of Chemistry, Nippon Roche Research Center, 200 Kajiwara, Kamakura, Kanagawa, Japan. | lld:pubmed |
| pubmed-article:12217374 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:12217374 | lld:chembl |
