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pubmed-article:12212126rdf:typepubmed:Citationlld:pubmed
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pubmed-article:12212126pubmed:issue5lld:pubmed
pubmed-article:12212126pubmed:dateCreated2002-9-5lld:pubmed
pubmed-article:12212126pubmed:abstractTextThe effects of Chinese medicine jiexinkang(JXK) on apoptosis of leukemic cells were studied by morphology approach and electrophoresis of DNA fragments. RESULTS: 1. The apoptotic cells and apoptotic bodies were found by electrical microscopy and the typical ladders of DNA fragments were detected by electrophoresis. 2. JXK induced apoptosis of leukemic cells(HL-60 and K562) in a certain range of concentration and at appropriate time. The time to K562 cell apoptosis was longer than that of HL-60 and its dosage was larger than that of HL-60. CONCLUSION: HL-60 and K562 leukemic cell apoptosis may be induced by JXK and there is correlation between dose and time. The study provides experimental evidences for the clinical treatment of leukemia.lld:pubmed
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pubmed-article:12212126pubmed:statusMEDLINElld:pubmed
pubmed-article:12212126pubmed:monthOctlld:pubmed
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pubmed-article:12212126pubmed:authorpubmed-author:BasV MVMlld:pubmed
pubmed-article:12212126pubmed:authorpubmed-author:QinQQlld:pubmed
pubmed-article:12212126pubmed:authorpubmed-author:XieZ XZXlld:pubmed
pubmed-article:12212126pubmed:authorpubmed-author:BaoY JYJlld:pubmed
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pubmed-article:12212126pubmed:pagination480-2lld:pubmed
pubmed-article:12212126pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:12212126pubmed:articleTitle[The effects of jiexinkang on the apoptosis of leukemic cells].lld:pubmed
pubmed-article:12212126pubmed:affiliationDepartment of Hematology, Xiangya Hospital, Hunan Medical University, Changsha 410008.lld:pubmed
pubmed-article:12212126pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12212126pubmed:publicationTypeEnglish Abstractlld:pubmed