| pubmed-article:12210881 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12210881 | lifeskim:mentions | umls-concept:C0021753 | lld:lifeskim |
| pubmed-article:12210881 | lifeskim:mentions | umls-concept:C0393571 | lld:lifeskim |
| pubmed-article:12210881 | lifeskim:mentions | umls-concept:C0678951 | lld:lifeskim |
| pubmed-article:12210881 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:12210881 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:12210881 | pubmed:dateCreated | 2002-9-4 | lld:pubmed |
| pubmed-article:12210881 | pubmed:abstractText | We studied genetic polymorphisms in the promoter region at position -511 of the interleukin (IL) -1beta gene (IL-1B-511) and at position -889 of the IL-1alpha gene (IL-1A-889), in 111 Japanese patients with multiple system atrophy (MSA) and 160 controls. The distribution of IL-1B-511 was significantly different between MSA patients and controls, because of the under-representation of patients with homozygotes for allele 2 (IL-1B-511*2), a high producer of IL-1beta. The frequency of IL-1A-889*2, a high secretor of IL-1alpha, was also decreased in MSA patients. Our findings suggest that abnormal cytokine expression may be implicated in the pathogenesis of MSA. | lld:pubmed |
| pubmed-article:12210881 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12210881 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12210881 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12210881 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12210881 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12210881 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12210881 | pubmed:issn | 0885-3185 | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:NakamuraShige... | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:NishimuraMasa... | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:MorinoHiroyuk... | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:MaruyamaHirof... | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:IzumiYuishinY | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:KawakamiHides... | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:KajiRyujiR | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:KunoSadakoS | lld:pubmed |
| pubmed-article:12210881 | pubmed:author | pubmed-author:KomureOsamuO | lld:pubmed |
| pubmed-article:12210881 | pubmed:copyrightInfo | Copyright 2002 Movement Disorder Society | lld:pubmed |
| pubmed-article:12210881 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12210881 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:12210881 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12210881 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12210881 | pubmed:pagination | 808-11 | lld:pubmed |
| pubmed-article:12210881 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:meshHeading | pubmed-meshheading:12210881... | lld:pubmed |
| pubmed-article:12210881 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12210881 | pubmed:articleTitle | Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy. | lld:pubmed |
| pubmed-article:12210881 | pubmed:affiliation | Department of Clinical Neuroscience, Tokushima University Hospital, Tokushima, Japan. m_nishim@clin.med.tokushima-u.ac.jp | lld:pubmed |
| pubmed-article:12210881 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12210881 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:3552 | entrezgene:pubmed | pubmed-article:12210881 | lld:entrezgene |
| entrez-gene:3553 | entrezgene:pubmed | pubmed-article:12210881 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:12210881 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:12210881 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12210881 | lld:pubmed |
