| pubmed-article:12207158 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C0002771 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C0033382 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C1709915 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C1549781 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:12207158 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:12207158 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:12207158 | pubmed:dateCreated | 2002-9-3 | lld:pubmed |
| pubmed-article:12207158 | pubmed:abstractText | It has been demonstrated that there are structural and functional similarities between interferon-alpha (INF-alpha) and endorphins. We have reported that there are distinct domains in the IFN-alpha molecule that mediate immune and analgesic effects, respectively, and that the opioid-like analgesic effect of IFN-alpha is mediated by the mu opioid receptor, thus inferring that the analgesic domain of IFN-alpha consists of Tyr(122) and the residues around Tyr(122) in the tertiary structure. The aim of this work was to further explore the molecular basis for the analgesic domain of IFN-alpha. | lld:pubmed |
| pubmed-article:12207158 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12207158 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12207158 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12207158 | pubmed:issn | 1021-7401 | lld:pubmed |
| pubmed-article:12207158 | pubmed:author | pubmed-author:ChenYi-ZhangY... | lld:pubmed |
| pubmed-article:12207158 | pubmed:author | pubmed-author:WangYun-XiaYX | lld:pubmed |
| pubmed-article:12207158 | pubmed:author | pubmed-author:SongLi-HuaLH | lld:pubmed |
| pubmed-article:12207158 | pubmed:author | pubmed-author:JiangChun-Lei... | lld:pubmed |
| pubmed-article:12207158 | pubmed:copyrightInfo | Copyright 2002 S. Karger AG, Basel | lld:pubmed |
| pubmed-article:12207158 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12207158 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:12207158 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12207158 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12207158 | pubmed:pagination | 5-8 | lld:pubmed |
| pubmed-article:12207158 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:meshHeading | pubmed-meshheading:12207158... | lld:pubmed |
| pubmed-article:12207158 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12207158 | pubmed:articleTitle | The analgesic domain of interferon-alpha2b contains an essential proline(39) residue. | lld:pubmed |
| pubmed-article:12207158 | pubmed:affiliation | Department of Neurobiology, Second Military Medical University, Shanghai, PR China. | lld:pubmed |
| pubmed-article:12207158 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12207158 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
