| pubmed-article:12188489 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12188489 | lifeskim:mentions | umls-concept:C0029463 | lld:lifeskim |
| pubmed-article:12188489 | lifeskim:mentions | umls-concept:C0022742 | lld:lifeskim |
| pubmed-article:12188489 | lifeskim:mentions | umls-concept:C0431085 | lld:lifeskim |
| pubmed-article:12188489 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:12188489 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:12188489 | pubmed:dateCreated | 2002-8-21 | lld:pubmed |
| pubmed-article:12188489 | pubmed:abstractText | We studied 55 patients with stage-IIB osteosarcoma around the knee with respect to the expression of matrix metalloproteinase (MMP)-9 in the surviving tumour cells in surgical resection specimens. They were followed up for a minimum of 2.5 years. Factors significantly associated with poor overall survival were a high serum level of alkaline phosphatase at diagnosis and tumour cells expressing MMP-9 in the resection specimens. The only factor strongly associated with disease-free survival was the immunohistochemical status of tumour cells for MMP-9 in the resection specimens. The percentage of necrosis after chemotherapy failed marginally to reach statistical significance. On Cox regression analysis only MMP-9 remained significant for overall and disease-free survival. | lld:pubmed |
| pubmed-article:12188489 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12188489 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12188489 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:12188489 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12188489 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12188489 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12188489 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12188489 | pubmed:issn | 0301-620X | lld:pubmed |
| pubmed-article:12188489 | pubmed:author | pubmed-author:TaylorSS | lld:pubmed |
| pubmed-article:12188489 | pubmed:author | pubmed-author:GrimerR JRJ | lld:pubmed |
| pubmed-article:12188489 | pubmed:author | pubmed-author:ManghamD CDC | lld:pubmed |
| pubmed-article:12188489 | pubmed:author | pubmed-author:ManionG LGL | lld:pubmed |
| pubmed-article:12188489 | pubmed:author | pubmed-author:DeshmukhN SNS | lld:pubmed |
| pubmed-article:12188489 | pubmed:author | pubmed-author:FoukasA FAF | lld:pubmed |
| pubmed-article:12188489 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12188489 | pubmed:volume | 84 | lld:pubmed |
| pubmed-article:12188489 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12188489 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12188489 | pubmed:pagination | 706-11 | lld:pubmed |
| pubmed-article:12188489 | pubmed:dateRevised | 2010-11-10 | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:meshHeading | pubmed-meshheading:12188489... | lld:pubmed |
| pubmed-article:12188489 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12188489 | pubmed:articleTitle | Stage-IIB osteosarcomas around the knee. A study of MMP-9 in surviving tumour cells. | lld:pubmed |
| pubmed-article:12188489 | pubmed:affiliation | Royal Orthopaedic Hospital, Birmingham, England. | lld:pubmed |
| pubmed-article:12188489 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12188489 | lld:pubmed |
