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pubmed-article:12186936pubmed:abstractTextRotavirus infection in children at risk of developing type 1 diabetes has been temporally associated with development of pancreatic islet autoantibodies. In this study, nonobese diabetic mice were shown to be susceptible to rhesus rotavirus infection and pancreatic islets from nonobese diabetic mice, nonobese diabetes-resistant mice, fetal pigs, and macaque monkeys supported various degrees of rotavirus growth. Human rotaviruses replicated in monkey islets only. This islet susceptibility shows that rotavirus infection of the pancreas in vivo might be possible.lld:pubmed
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pubmed-article:12186936pubmed:authorpubmed-author:LINS CSClld:pubmed
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pubmed-article:12186936pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:12186936pubmed:articleTitleGrowth of rotaviruses in primary pancreatic cells.lld:pubmed
pubmed-article:12186936pubmed:affiliationDepartment of Microbiology and Immunology, The University of Melbourne, Royal Parade, Victoria 3010, Australia. barbarac@unimelb.edu.aulld:pubmed
pubmed-article:12186936pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12186936pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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