Source:http://linkedlifedata.com/resource/pubmed/id/12183777
| Subject | Predicate | Object | Context |
|---|---|---|---|
| pubmed-article:12183777 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12183777 | lifeskim:mentions | umls-concept:C0023216 | lld:lifeskim |
| pubmed-article:12183777 | lifeskim:mentions | umls-concept:C0019010 | lld:lifeskim |
| pubmed-article:12183777 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:12183777 | lifeskim:mentions | umls-concept:C0741847 | lld:lifeskim |
| pubmed-article:12183777 | lifeskim:mentions | umls-concept:C0549193 | lld:lifeskim |
| pubmed-article:12183777 | pubmed:dateCreated | 2002-11-26 | lld:pubmed |
| pubmed-article:12183777 | pubmed:abstractText | Early postoperative changes in the hemodynamic parameters of infrainguinal bypass grafts in diabetics have not been well defined. We undertook this study to better define such changes in duplex-derived velocities and waveforms, and correlate any observed changes with intermediate-term outcomes. A prospective study of 68 primary vein bypasses for limb salvage was carried out, with scans obtained intraoperatively, daily until discharge, and at 8- to 12-weeks intervals. During follow-up (12 +/- 6 months), 20 grafts developed stenoses, 17 occluded, and 8 limbs were amputated. Most grafts show a variant of a biphasic waveform intraoperatively at the mid-graft (MG) and distal graft (DG) levels (54% and 57%); 65% of waveforms remain unchanged during the first week, and 54% remain unchanged at 3 months. No duplex-derived factors were predictive of the development of stenoses. A number of parameters were predictive of ultimate graft thrombosis. Intraoperative MG velocity was higher in grafts that eventually remained patent (83 +/- 36 vs. 60 +/- 29 cm/sec; p <0.025). Grafts that remained patent also had a much lower decline in DG and distal native (DN) velocities from immediately postoperative to 8-12 weeks later, than grafts that eventually thrombosed (-3 +/- 35 vs. -44 +/- 43 cm/sec for DG, p <0.001; and -17 +/- 66 vs. -76 +/- 53 cm/sec for DN, p <0.04 respectively). In terms of limb salvage, when the MG or DG waveform worsened (from postoperation to 12 weeks later), amputation was more likely than when it remained unchanged or improved (MG 67% vs. 9% limb loss, p <0.04; DG 43% vs. 8% limb loss, p <0.04). We conclude that intensive graft duplex surveillance does not identify grafts likely to develop stenoses. However, a number of features allow the prediction of ultimate graft failure or limb loss. | lld:pubmed |
| pubmed-article:12183777 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12183777 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12183777 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:Toursarkissia... | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:D'AyalaMarcus... | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:StefanidisDim... | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:ShiremanPaula... | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:SchoolfieldJo... | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:SykesMellick... | lld:pubmed |
| pubmed-article:12183777 | pubmed:author | pubmed-author:HaginoRyan... | lld:pubmed |
| pubmed-article:12183777 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12183777 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12183777 | pubmed:pagination | 601-7 | lld:pubmed |
| pubmed-article:12183777 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:12183777 | pubmed:articleTitle | Early duplex-derived hemodynamic parameters after lower extremity bypass in diabetics: implications for mid-term outcomes. | lld:pubmed |
| pubmed-article:12183777 | pubmed:affiliation | Division of Vascular Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA. toursarkiss@uthscsa.edu | lld:pubmed |