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pubmed-article:12173321pubmed:abstractTextThe authors previously found the I1307K adenomatous polyposis coli (APC) gene variant in 5% of Ashkenazi control participants, in 15.4% of those who had familial colorectal neoplasia, but also in 1.6% of non-Ashkenazi control participants. In this study, they evaluated its use in a screening program for familial colorectal neoplasia and examined for a founder effect.lld:pubmed
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pubmed-article:12173321pubmed:articleTitleClinical and screening implications of the I1307K adenomatous polyposis coli gene variant in Israeli Ashkenazi Jews with familial colorectal neoplasia. Evidence for a founder effect.lld:pubmed
pubmed-article:12173321pubmed:affiliationDepartment of Gastroenterology, Tel Aviv Medical Center, 6 Weizmann Street, 64239 Tel Aviv, Israel. rozen@tasmc.health.gov.illld:pubmed
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