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pubmed-article:12171955pubmed:abstractTextIntestinal metaplasia (IM) at the cardia is likely to be a precursor of cardia cancer. Previous work has shown that it is associated with chronic inflammation attributable to either gastro-oesophageal reflux disease (GORD) or Helicobacter pylori infection. An alternative aetiological factor is bile reflux. Duodenogastric reflux brings about histological changes in the gastric mucosa that can be graded and used to calculate a bile reflux index (BRI). We used the BRI to assess whether reflux of bile plays a part in the development of cardia IM.lld:pubmed
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pubmed-article:12171955pubmed:articleTitleBile reflux gastritis and intestinal metaplasia at the cardia.lld:pubmed
pubmed-article:12171955pubmed:affiliationAcademic Unit of Pathology, University of Leeds, UK. miked@pathology.leeds.ac.uklld:pubmed
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