| pubmed-article:12147376 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C0007113 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C1559154 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C0681842 | lld:lifeskim |
| pubmed-article:12147376 | lifeskim:mentions | umls-concept:C1136216 | lld:lifeskim |
| pubmed-article:12147376 | pubmed:issue | 9329 | lld:pubmed |
| pubmed-article:12147376 | pubmed:dateCreated | 2002-7-30 | lld:pubmed |
| pubmed-article:12147376 | pubmed:abstractText | Prediction of tumour response before onset of treatment could have considerable clinical benefit. Since the apparent diffusion coefficient (ADC) of a tumour's water content can show the extent of necrosis, we looked for a possible correlation of ADC with response to treatment. We measured mean tumour water ADC before and after chemotherapy and chemoradiation in 14 patients with locally advanced rectal cancer, with a quantitative magnetic resonance diffusion imaging sequence. We found a strong negative correlation between mean pretreatment tumour water ADC and percentage size change of tumours after chemotherapy (r=-0.67, p=0.01) and chemoradiation (r=-0.83, p=0.001). Persistence of low ADC in responders after chemotherapy could represent loss of a non-viable fraction of the treated tumour. | lld:pubmed |
| pubmed-article:12147376 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12147376 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12147376 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:12147376 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12147376 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12147376 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12147376 | pubmed:issn | 0140-6736 | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:PadhaniAnwarA | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:Dzik-JuraszAn... | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:DomenigClaudi... | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:GeorgeMarkM | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:WolberJanJ | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:BrownGinaG | lld:pubmed |
| pubmed-article:12147376 | pubmed:author | pubmed-author:DoranSimonS | lld:pubmed |
| pubmed-article:12147376 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12147376 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:12147376 | pubmed:volume | 360 | lld:pubmed |
| pubmed-article:12147376 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12147376 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12147376 | pubmed:pagination | 307-8 | lld:pubmed |
| pubmed-article:12147376 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:meshHeading | pubmed-meshheading:12147376... | lld:pubmed |
| pubmed-article:12147376 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12147376 | pubmed:articleTitle | Diffusion MRI for prediction of response of rectal cancer to chemoradiation. | lld:pubmed |
| pubmed-article:12147376 | pubmed:affiliation | UK Cancer Research Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Royal Marsden NHS Trust, Downs Road, Sutton SM2 5PT, UK. andrzej@icr.ac.uk | lld:pubmed |
| pubmed-article:12147376 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12147376 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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