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| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0013216 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0007131 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0008838 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0045093 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C1333355 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0205251 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0439590 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:12114432 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:12114432 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:12114432 | pubmed:dateCreated | 2002-7-12 | lld:pubmed |
| pubmed-article:12114432 | pubmed:abstractText | Overexpression of the excision repair cross-complementing 1 (ERCC1) gene, which is crucial in the repair of cisplatin (CDDP)-DNA adducts, is reported to negatively influence the effectiveness of CDDP-based therapy for gastric and ovarian cancers. Recent evidence indicates that Gemcitabine (Gem) may modulate ERCC1 nucleotide excision repair activity, and down-regulation of DNA repair activity by ERCC1 antisense RNA reportedly inhibits synergism of CDDP/Gem. We investigated whether ERCC1 mRNA expression levels were associated with clinical outcomes after treatment with a combination Gem/CDDP regimen for patients with advanced stage non-small cell lung cancer (NSCLC). | lld:pubmed |
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| pubmed-article:12114432 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:12114432 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12114432 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12114432 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12114432 | pubmed:issn | 1078-0432 | lld:pubmed |
| pubmed-article:12114432 | pubmed:author | pubmed-author:BrabenderJanJ | lld:pubmed |
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| pubmed-article:12114432 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12114432 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:12114432 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12114432 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12114432 | pubmed:pagination | 2286-91 | lld:pubmed |
| pubmed-article:12114432 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:12114432 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12114432 | pubmed:articleTitle | Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer. | lld:pubmed |
| pubmed-article:12114432 | pubmed:affiliation | University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA. | lld:pubmed |
| pubmed-article:12114432 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12114432 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:12114432 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12114432 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:12114432 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:12114432 | pubmed:publicationType | Multicenter Study | lld:pubmed |
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