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pubmed-article:12114336pubmed:abstractTextHeparin-induced thrombocytopenia (HIT) is an immune-mediated adverse drug reaction associated with a decrease of platelet counts that usually begins after at least 5 days of heparin treatment. Uncertainty exists about the risk of early onset of HIT (ie, < 5 days) in relation to previous heparin exposure. We therefore analyzed the temporal pattern of thrombocytopenia in patients with laboratory-confirmed HIT to assess whether patients with previous heparin exposure have an increased risk of early onset of HIT.lld:pubmed
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pubmed-article:12114336pubmed:articleTitleHeparin-induced thrombocytopenia: temporal pattern of thrombocytopenia in relation to initial use or reexposure to heparin.lld:pubmed
pubmed-article:12114336pubmed:affiliationDepartment of Immunology and Transfusion Medicine, Ernst-Moritz-Arndt University, Greifswald, Germany.lld:pubmed
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