| pubmed-article:12062363 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C0023976 | lld:lifeskim |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C1416572 | lld:lifeskim |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C0599155 | lld:lifeskim |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:12062363 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:12062363 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:12062363 | pubmed:dateCreated | 2002-6-13 | lld:pubmed |
| pubmed-article:12062363 | pubmed:abstractText | In a 32-year-old woman with marked QT prolongation (QTc=0.61 s) and repeated episodes of syncope, we identified a single pertinent base substitution (G to A at 1909) in HERG by genetic analysis. This novel missense mutation is predicted to cause an amino acid substitution of lysine for glutamic acid at position 637 (E637K) in the pore-S6 loop. Therefore, we investigated the role of a glutamic acid at the vicinity of the pore in HERG channels by mutating it to a lysine. | lld:pubmed |
| pubmed-article:12062363 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12062363 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12062363 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12062363 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12062363 | pubmed:issn | 0008-6363 | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:MabuchiHirosh... | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:ShimizuMasami... | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:InoHidekazuH | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:YamaguchiMasa... | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:HayashiKenshi... | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:HoshiNaotoN | lld:pubmed |
| pubmed-article:12062363 | pubmed:author | pubmed-author:HigashidaHaru... | lld:pubmed |
| pubmed-article:12062363 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12062363 | pubmed:volume | 54 | lld:pubmed |
| pubmed-article:12062363 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12062363 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12062363 | pubmed:pagination | 67-76 | lld:pubmed |
| pubmed-article:12062363 | pubmed:dateRevised | 2008-10-28 | lld:pubmed |
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| pubmed-article:12062363 | pubmed:meshHeading | pubmed-meshheading:12062363... | lld:pubmed |
| pubmed-article:12062363 | pubmed:meshHeading | pubmed-meshheading:12062363... | lld:pubmed |
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| pubmed-article:12062363 | pubmed:meshHeading | pubmed-meshheading:12062363... | lld:pubmed |
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| pubmed-article:12062363 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12062363 | pubmed:articleTitle | Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome. | lld:pubmed |
| pubmed-article:12062363 | pubmed:affiliation | Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University 13-1, Takara-machi, Ishikawa 920-8640, Japan. kenshi@im2.m.kanazawa-u.ac.jp | lld:pubmed |
| pubmed-article:12062363 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12062363 | pubmed:publicationType | Case Reports | lld:pubmed |
| literatureCitation:101_1206... | literatureCitation:pubmed | pubmed-article:12062363 | lld:drugbank |
| entrez-gene:3757 | entrezgene:pubmed | pubmed-article:12062363 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12062363 | lld:pubmed |
