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pubmed-article:12058319pubmed:abstractTextFive new compounds, two degraded terpene glycosides, dasycarpusides A and B (1, 2), and three phenolic glycosides, 2-methoxy-4-hydroxymethylphenol 1-O-alpha-rhamnopyranosyl-(1"-->6')- beta-glucopyranoside ( 3), 2-methoxy-4-acetylphenol 1-O-alpha-rhamnopyranosyl-(1"-->6')-beta-glucopyranoside (4), and 2-methoxy-4-(8-hydroxyethyl)-phenol 1-O-alpha-rhamnopyranosyl-(1"-->6')-beta-glucopyranoside (5), were isolated from the water-soluble constituents of the root bark of Dictamnus dasycarpus Turcz.(Rutaceae). Their structures were elucidated by spectroscopic analysis and chemical evidence. Moreover, it was found that dasycarpuside A (1) showed weak cytotoxic activity against A-549 (human lung adenocarcinoma) cell line, while 4 and 5 showed more remarkable activity of inhibiting the proliferation of T-cells in vitro.lld:pubmed
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pubmed-article:12058319pubmed:authorpubmed-author:ChangJunJlld:pubmed
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pubmed-article:12058319pubmed:pagination425-9lld:pubmed
pubmed-article:12058319pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:12058319pubmed:articleTitleCytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dictamnus dasycarpus.lld:pubmed
pubmed-article:12058319pubmed:affiliationShanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China.lld:pubmed
pubmed-article:12058319pubmed:publicationTypeJournal Articlelld:pubmed