| pubmed-article:12056805 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12056805 | lifeskim:mentions | umls-concept:C0327431 | lld:lifeskim |
| pubmed-article:12056805 | lifeskim:mentions | umls-concept:C0042479 | lld:lifeskim |
| pubmed-article:12056805 | lifeskim:mentions | umls-concept:C0027934 | lld:lifeskim |
| pubmed-article:12056805 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:12056805 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:12056805 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:12056805 | pubmed:dateCreated | 2002-6-11 | lld:pubmed |
| pubmed-article:12056805 | pubmed:abstractText | A neurotoxin, Oh9-1, from the venom of Ophiophagus hannah was isolated by a combination of ion-exchange chromatography and reverse phase HPLC. Amino acid sequence analysis revealed that Oh9-1 consists of 57 amino acids and eight cysteine residues. This protein was mainly constituted with beta-sheet as evidenced by CD spectrum. Oh9-1 inhibited carbachol-induced muscle contraction in an irreversible manner and the dose for achieving 50% inhibition was approximately fourfold that of alpha-bungarotoxin. Since the residues in alpha-neurotoxins closely involve in the binding with acetylcholine receptors are not highly conserved in this toxin molecule, Oh9-1 represents a novel type of neurotoxin structurally distinct from alpha-neurotoxins. | lld:pubmed |
| pubmed-article:12056805 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12056805 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12056805 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12056805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12056805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12056805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12056805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12056805 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12056805 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:12056805 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:12056805 | pubmed:author | pubmed-author:HuangHsien-Bi... | lld:pubmed |
| pubmed-article:12056805 | pubmed:author | pubmed-author:LinShinne-Ren... | lld:pubmed |
| pubmed-article:12056805 | pubmed:author | pubmed-author:ChangLong-Sen... | lld:pubmed |
| pubmed-article:12056805 | pubmed:author | pubmed-author:LiouJau-Cheng... | lld:pubmed |
| pubmed-article:12056805 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12056805 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:12056805 | pubmed:volume | 294 | lld:pubmed |
| pubmed-article:12056805 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12056805 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12056805 | pubmed:pagination | 574-8 | lld:pubmed |
| pubmed-article:12056805 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:meshHeading | pubmed-meshheading:12056805... | lld:pubmed |
| pubmed-article:12056805 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12056805 | pubmed:articleTitle | Purification and characterization of a neurotoxin from the venom of Ophiophagus hannah (king cobra). | lld:pubmed |
| pubmed-article:12056805 | pubmed:affiliation | Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung 804, Taiwan. lschang@mail.nsysu.edu.tw | lld:pubmed |
| pubmed-article:12056805 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12056805 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
