Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production.

Source:http://linkedlifedata.com/resource/pubmed/id/12048239

Proc. Natl. Acad. Sci. U.S.A. 2002 Jun 11 99 12 8025-30

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PMID
12048239