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pubmed-article:12047512pubmed:abstractTextInflammatory cytokines in platelet concentrates (PC) may cause side-effects such as febrile non-haemolytic transfusion reactions. The maximum white blood cell (WBC) content tolerable to avoid the accumulation of cytokines, and whether these cytokines originate from degranulating leucocytes or de novo synthesis during storage, had not been investigated prior to this study.lld:pubmed
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pubmed-article:12047512pubmed:articleTitleEvidence for de novo synthesis of cytokines and chemokines in platelet concentrates.lld:pubmed
pubmed-article:12047512pubmed:affiliationInstitute of Immunology and Transfusion Medicine, University of Lübeck School of Medicine, Germany. hartwig@immu.mu-luebeck.delld:pubmed
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