| pubmed-article:12039742 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0023861 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0439605 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0200928 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0200898 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0182400 | lld:lifeskim |
| pubmed-article:12039742 | lifeskim:mentions | umls-concept:C0205195 | lld:lifeskim |
| pubmed-article:12039742 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:12039742 | pubmed:dateCreated | 2002-5-31 | lld:pubmed |
| pubmed-article:12039742 | pubmed:abstractText | To improve our understanding of the genetic links between strains originating from food and strains responsible for human diseases, we studied the genetic diversity and population structure of 130 epidemiologically unrelated Listeria monocytogenes strains. Strains were isolated from different sources and ecosystems in which the bacterium is commonly found. We used rRNA gene restriction fragment length polymorphism analysis with two endonucleases and random multiprimer DNA analysis with seven oligonucleotide primers to study multiple genetic features of each strain. We used three clustering methods to identify genetic links between individual strains and to determine the precise genetic structure of the population. The combined results confirmed that L. monocytogenes strains can be divided into two major phylogenetic divisions. The method used allowed us to demonstrate that the genetic structure and diversity of the two phylogenetic divisions differ. Division I is the most homogeneous and can easily be divided into subgroups with dissimilarity distances of less than 0.30. Each of these subgroups mainly, or exclusively, contains a single serotype (1/2b, 4b, 3b, or 4a). The serotype 4a lineage appears to form a branch that is highly divergent from the phylogenetic group containing serotypes 1/2b, 4b, and 3b. Division II contains strains of serotypes 1/2a, 1/2c, and 3a. It exhibits more genetic diversity with no peculiar clustering. The fact that division II is more heterogeneous than division I suggests that division II evolved from a common ancestor earlier than division I. A significant association was found between division I and human strains, suggesting that strains from division I are better adapted to human hosts. | lld:pubmed |
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| pubmed-article:12039742 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12039742 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12039742 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12039742 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12039742 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:12039742 | pubmed:issn | 0099-2240 | lld:pubmed |
| pubmed-article:12039742 | pubmed:author | pubmed-author:AudurierAA | lld:pubmed |
| pubmed-article:12039742 | pubmed:author | pubmed-author:QuentinRR | lld:pubmed |
| pubmed-article:12039742 | pubmed:author | pubmed-author:Marquet-Van... | lld:pubmed |
| pubmed-article:12039742 | pubmed:author | pubmed-author:LanottePP | lld:pubmed |
| pubmed-article:12039742 | pubmed:author | pubmed-author:MereghettiLL | lld:pubmed |
| pubmed-article:12039742 | pubmed:author | pubmed-author:Savoye-Marczu... | lld:pubmed |
| pubmed-article:12039742 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12039742 | pubmed:volume | 68 | lld:pubmed |
| pubmed-article:12039742 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12039742 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12039742 | pubmed:pagination | 2849-57 | lld:pubmed |
| pubmed-article:12039742 | pubmed:dateRevised | 2010-9-14 | lld:pubmed |
| pubmed-article:12039742 | pubmed:meshHeading | pubmed-meshheading:12039742... | lld:pubmed |
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| pubmed-article:12039742 | pubmed:meshHeading | pubmed-meshheading:12039742... | lld:pubmed |
| pubmed-article:12039742 | pubmed:meshHeading | pubmed-meshheading:12039742... | lld:pubmed |
| pubmed-article:12039742 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12039742 | pubmed:articleTitle | Combined ribotyping and random multiprimer DNA analysis to probe the population structure of Listeria monocytogenes. | lld:pubmed |
| pubmed-article:12039742 | pubmed:affiliation | Département de Microbiologie Médicale et Moléculaire, Unité de Bactériologie, Faculté de Médecine de Tours, Tours, France. laurent.mereghetti@med.univ-tours.fr | lld:pubmed |
| pubmed-article:12039742 | pubmed:publicationType | Journal Article | lld:pubmed |
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