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pubmed-article:12011148pubmed:abstractTextThe mismatch repair gene, MLH1, appears to occur as two main haplotypes at least in white populations. These are referred to as A and G types with reference to the A/G polymorphism at IVS14-19. On the basis of preliminary experimental data, we hypothesised that deviations from the expected frequency of these two haplotypes could exist in carriers of disease associated MLH1 germline mutations.lld:pubmed
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pubmed-article:12011148pubmed:articleTitleAn MLH1 haplotype is over-represented on chromosomes carrying an HNPCC predisposing mutation in MLH1.lld:pubmed
pubmed-article:12011148pubmed:affiliationUnit of Genetics, Institut Central des Hôpitaux Valaisans, Sion, Switzerland. pierre.hutter@ichv.vsnet.chlld:pubmed
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