| pubmed-article:11997512 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C0085862 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1299583 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C0242210 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1424656 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1148856 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1608386 | lld:lifeskim |
| pubmed-article:11997512 | lifeskim:mentions | umls-concept:C1549571 | lld:lifeskim |
| pubmed-article:11997512 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:11997512 | pubmed:dateCreated | 2002-5-8 | lld:pubmed |
| pubmed-article:11997512 | pubmed:abstractText | The 3' poly(A) tail of eukaryotic mRNAs plays an important role in the regulation of translation. The poly(A) binding protein (PABP) interacts with eukaryotic initiation factor 4G (eIF4G), a component of the eIF4F complex, which binds to the 5' cap structure. The PABP-eIF4G interaction brings about the circularization of the mRNA by joining its 5' and 3' termini, thereby stimulating mRNA translation. The activity of PABP is regulated by two interacting proteins, Paip1 and Paip2. To study the mechanism of the Paip1-PABP interaction, far-Western, glutathione S-transferase pull-down, and surface plasmon resonance experiments were performed. Paip1 contains two binding sites for PABP, PAM1 and PAM2 (for PABP-interacting motifs 1 and 2). PAM2 consists of a 15-amino-acid stretch residing in the N terminus, and PAM1 encompasses a larger C-terminal acidic-amino-acid-rich region. PABP also contains two Paip1 binding sites, one located in RNA recognition motifs 1 and 2 and the other located in the C-terminal domain. Paip1 binds to PABP with a 1:1 stoichiometry and an apparent K(d) of 1.9 nM. | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11997512 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11997512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11997512 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11997512 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:11997512 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:11997512 | pubmed:author | pubmed-author:SonenbergNahu... | lld:pubmed |
| pubmed-article:11997512 | pubmed:author | pubmed-author:RoyGuylaineG | lld:pubmed |
| pubmed-article:11997512 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:11997512 | pubmed:author | pubmed-author:KhaleghpourKi... | lld:pubmed |
| pubmed-article:11997512 | pubmed:author | pubmed-author:KahvejianAvak... | lld:pubmed |
| pubmed-article:11997512 | pubmed:author | pubmed-author:O'Connor-McCo... | lld:pubmed |
| pubmed-article:11997512 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11997512 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:11997512 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11997512 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11997512 | pubmed:pagination | 3769-82 | lld:pubmed |
| pubmed-article:11997512 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:meshHeading | pubmed-meshheading:11997512... | lld:pubmed |
| pubmed-article:11997512 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:11997512 | pubmed:articleTitle | Paip1 interacts with poly(A) binding protein through two independent binding motifs. | lld:pubmed |
| pubmed-article:11997512 | pubmed:affiliation | Department of Biochemistry and McGill Cancer Centre, McGill University, Montréal, Québec, Canada H3G 1Y6. | lld:pubmed |
| pubmed-article:11997512 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11997512 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:11997512 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:26986 | entrezgene:pubmed | pubmed-article:11997512 | lld:entrezgene |
| entrez-gene:10605 | entrezgene:pubmed | pubmed-article:11997512 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11997512 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11997512 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11997512 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11997512 | lld:pubmed |
