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pubmed-article:11983082pubmed:abstractTextWe investigated the distribution of troponin C.I and troponin I along tropomyosin-actin filaments by immunoelectron microscopy and found that anti-troponin I antibody formed transverse striations at 38 nm intervals along the bundle of filaments of both troponin C.I-tropomyosin-actin and troponin I-tropomyosin-actin. Since the length of 38 nm corresponds to the repeating period of filamentous tropomyosin along actin double strands, the present study indicates that troponin I is located at a specific region of each tropomyosin, suggesting that a specific interaction between troponin I and tropomyosin is involved in determining the periodic distribution of troponin I along tropomyosin-actin filaments.lld:pubmed
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pubmed-article:11983082pubmed:authorpubmed-author:OhtsukiIwaoIlld:pubmed
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pubmed-article:11983082pubmed:dateRevised2011-11-17lld:pubmed
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pubmed-article:11983082pubmed:articleTitlePeriodic binding of troponin C.I and troponin I to tropomyosin-actin filaments.lld:pubmed
pubmed-article:11983082pubmed:affiliationDepartment of Pharmacology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan. iohtsuki@po1.dti2.ne.jplld:pubmed
pubmed-article:11983082pubmed:publicationTypeJournal Articlelld:pubmed