pubmed-article:11977486 | pubmed:abstractText | The aim of this study was to determine the spectrum of bacteria isolated in patients with non-TB respiratory disorders, in order to find the frequency of germs isolated globally and in each of the 6 clinical syndromes: suppurations, chronic obstructive diseases exacerbations (COPD, bronchial asthma), pneumopathies, post-TB syndromes, tumors and interstitial lung diseases. We found the greatest global frequency in anaerobes (35%). This is in concordance with the high frequency of broncho-pulmonary suppurations (51% of the cases studied). In second place comes Ps. aeruginosa (18%), followed by Str. Pneumoniae (16%), H. influenzae (11%) and Klebsiella pn. (10%). Considering the germs identified in the various clinical syndromes, we found a high frequency of anaerobes associated to suppurations (51%), interstitial lung diseases (43%) and tumors (37%), while Ps. aeruginosa is first in post-TB syndromes (50%) and COPD exacerbations (21%), equal to H. influenzae. In pneumonias, Str. Pneumoniae was most frequently isolated (38%) followed by H. influenzae (25%). The susceptibility testing of strains of Klebsiella and Ps. aeruginosa revealed the increasing tendency to resistance to broad spectrum antibiotics, especially for Ps. aeruginosa, with consecutive difficulties in finding the appropriate treatment. | lld:pubmed |