pubmed-article:11969245 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11969245 | lifeskim:mentions | umls-concept:C0001792 | lld:lifeskim |
pubmed-article:11969245 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:11969245 | lifeskim:mentions | umls-concept:C0206111 | lld:lifeskim |
pubmed-article:11969245 | lifeskim:mentions | umls-concept:C0597879 | lld:lifeskim |
pubmed-article:11969245 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:11969245 | pubmed:dateCreated | 2002-4-23 | lld:pubmed |
pubmed-article:11969245 | pubmed:abstractText | The distribution of the calcium binding protein neurocalcin a has been examined in the enteric nervous system of young adult (3 months) and aged (24+ months) male rats by immunofluorescence. Neurocalcin-immunoreactive (NC-ir) neurons were observed in the submucous and myenteric plexuses throughout the gastrointestinal tract from the oesophagus to the distal large intestine. NC-ir nerve terminals were also seen on NC-ir and NC-negative neurons. Semiquantitative estimates revealed fewer NC-ir neurons in the submucous plexus than in the myenteric plexus. The greatest occurrence of NC-ir neurons was in the small and large intestine. NC-ir axons were seen in the mucosa and also in between the ganglia of the myenteric plexus. In the aged rats, there were no discernible changes in the numbers of NC-ir neurons in th e oesophagus and stomach, with an increase in the pylorus and slight decreases in the small and large intestines. No decrease in NC-ir was observed in the distal large intestine. NC-ir neurons never contained lipofuscin age pigment and many enteric neuro ns devoid of NC-ir contained age pigment. Like other previously investigated calcium-binding proteins in enteric neurons, the distribution of NC shows much variability from one part of the intestine to another. The observed slight decreases in the number of NC-ir enteric neurons in aged rats may compromise the regulation of calcium in these neurons. | lld:pubmed |
pubmed-article:11969245 | pubmed:language | eng | lld:pubmed |
pubmed-article:11969245 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11969245 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11969245 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11969245 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11969245 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11969245 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11969245 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11969245 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11969245 | pubmed:month | Feb | lld:pubmed |
pubmed-article:11969245 | pubmed:issn | 0143-4160 | lld:pubmed |
pubmed-article:11969245 | pubmed:author | pubmed-author:HidakaHH | lld:pubmed |
pubmed-article:11969245 | pubmed:author | pubmed-author:SanterR MRM | lld:pubmed |
pubmed-article:11969245 | pubmed:author | pubmed-author:CornsR ARA | lld:pubmed |
pubmed-article:11969245 | pubmed:copyrightInfo | Copyright 2002 Elsevier Science Ltd. All rights reserved. | lld:pubmed |
pubmed-article:11969245 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11969245 | pubmed:volume | 31 | lld:pubmed |
pubmed-article:11969245 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11969245 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11969245 | pubmed:pagination | 53-8 | lld:pubmed |
pubmed-article:11969245 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:11969245 | pubmed:year | 2002 | lld:pubmed |
pubmed-article:11969245 | pubmed:articleTitle | Neurocalcin-alpha immunoreactivity in the enteric nervous system of young and aged rats. | lld:pubmed |
pubmed-article:11969245 | pubmed:affiliation | School of Biosciences, University of Wales Cardiff, Cardiff, UK. | lld:pubmed |
pubmed-article:11969245 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11969245 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:24877 | entrezgene:pubmed | pubmed-article:11969245 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11969245 | lld:entrezgene |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11969245 | lld:pubmed |