| pubmed-article:11931757 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11931757 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:11931757 | lifeskim:mentions | umls-concept:C0288422 | lld:lifeskim |
| pubmed-article:11931757 | lifeskim:mentions | umls-concept:C0598312 | lld:lifeskim |
| pubmed-article:11931757 | lifeskim:mentions | umls-concept:C1519749 | lld:lifeskim |
| pubmed-article:11931757 | lifeskim:mentions | umls-concept:C1704686 | lld:lifeskim |
| pubmed-article:11931757 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
| pubmed-article:11931757 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:11931757 | pubmed:dateCreated | 2002-4-4 | lld:pubmed |
| pubmed-article:11931757 | pubmed:abstractText | Eukaryotic cells possess overlapping mechanisms to ensure that DNA replication is restricted to the S phase of the cell cycle. The levels of hOrc1p, the largest subunit of the human origin recognition complex, vary during the cell division cycle. In rapidly proliferating cells, hOrc1p is expressed and targeted to chromatin as cells exit mitosis and prereplicative complexes are formed. Later, as cyclin A accumulates and cells enter S phase, hOrc1p is ubiquitinated on chromatin and then degraded. hOrc1p destruction occurs through the proteasome and is signaled in part by the SCF(Skp2) ubiquitin-ligase complex. Other hORC subunits are stable throughout the cell cycle. The regulation of hOrc1p may be an important mechanism in maintaining the ploidy in human cells. | lld:pubmed |
| pubmed-article:11931757 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11931757 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11931757 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11931757 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:11931757 | pubmed:issn | 1097-2765 | lld:pubmed |
| pubmed-article:11931757 | pubmed:author | pubmed-author:StillmanBruce... | lld:pubmed |
| pubmed-article:11931757 | pubmed:author | pubmed-author:KimSo-YoungSY | lld:pubmed |
| pubmed-article:11931757 | pubmed:author | pubmed-author:TanseyWilliam... | lld:pubmed |
| pubmed-article:11931757 | pubmed:author | pubmed-author:MéndezJuanJ | lld:pubmed |
| pubmed-article:11931757 | pubmed:author | pubmed-author:Zou-YangX... | lld:pubmed |
| pubmed-article:11931757 | pubmed:author | pubmed-author:HidakaMasumiM | lld:pubmed |
| pubmed-article:11931757 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11931757 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:11931757 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11931757 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11931757 | pubmed:pagination | 481-91 | lld:pubmed |
| pubmed-article:11931757 | pubmed:dateRevised | 2011-10-27 | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:meshHeading | pubmed-meshheading:11931757... | lld:pubmed |
| pubmed-article:11931757 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:11931757 | pubmed:articleTitle | Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. | lld:pubmed |
| pubmed-article:11931757 | pubmed:affiliation | Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. | lld:pubmed |
| pubmed-article:11931757 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11931757 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11931757 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:11931757 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:890 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:990 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:1017 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:1026 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:1027 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:5925 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:6502 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:7314 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:7316 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4171 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4172 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4173 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4174 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4175 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4176 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4998 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:4999 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:5000 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:5001 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:6233 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:7311 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:23594 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:23595 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:51343 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:81620 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| entrez-gene:84515 | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11931757 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11931757 | lld:pubmed |
