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pubmed-article:11904318pubmed:abstractTextGrowth hormone (GH) may be associated with the development of colorectal tumors directly and/or indirectly via an increased plasma level of insulin-like growth factor-I (IGF-I), which has been associated with colorectal cancer risk. Because a T-to-A polymorphism in the human GH1 gene at position 1663 is putatively associated with lower levels of GH and IGF-I, we investigated the relationship of this polymorphism to the risk of colorectal neoplasia.lld:pubmed
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pubmed-article:11904318pubmed:articleTitleAssociation of a common polymorphism in the human GH1 gene with colorectal neoplasia.lld:pubmed
pubmed-article:11904318pubmed:affiliationEtiology Program, Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Suite 407, Honolulu, HI 96813, USA. loic@crch.Hawaii.edulld:pubmed
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