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pubmed-article:11898457pubmed:abstractTextThe diagnosis of extrapulmonary tuberculosis including neurotuberculosis is difficult because of the low yield of culture positivity for Mycobacterium tuberculosis (M. tb). Serodiagnosis has emerged as a useful aid to the diagnosis of extrapulmonary tuberculosis. The utility and efficacy of detection of antimycobacterial antibodies to A-60 antigen in serum and/or cerebrospinal fluid (CSF) was analysed in 100 patients-neurotuberculosis-72, abdominal tuberculosis-12 and others-16. The overall positivity rate for the test was 75%. The positivity rate of the test in serum and/or CSF was 79.2% (57 of 72) in neurotuberculosis and 62.5% (10 of 16) for other forms of extrapulmonary tuberculosis. The positivity rate for antimycobacterial antibodies was higher for patients with tubercular meningitis -94.7%. To conclude, testing for antimycobacterial antibodies to A-60 antigen is a useful adjunct in the diagnosis of extrapulmonary tuberculosis especially neurotuberculosis.lld:pubmed
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pubmed-article:11898457pubmed:authorpubmed-author:SinghN PNPlld:pubmed
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pubmed-article:11898457pubmed:authorpubmed-author:BavejaU KUKlld:pubmed
pubmed-article:11898457pubmed:authorpubmed-author:AnuradhaSSlld:pubmed
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pubmed-article:11898457pubmed:pagination12-6lld:pubmed
pubmed-article:11898457pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:11898457pubmed:year2001lld:pubmed
pubmed-article:11898457pubmed:articleTitleSerodiagnosis of extra pulmonary tuberculosis using A-60 antigen.lld:pubmed
pubmed-article:11898457pubmed:affiliationDepartment of Medicine & Microbiology, Maulana Azad Medical College & Associated Lok Nayak Jaiprakash Hospital, New Delhi.lld:pubmed
pubmed-article:11898457pubmed:publicationTypeJournal Articlelld:pubmed
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