| pubmed-article:11818163 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0043167 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0035243 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0042210 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0805586 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C1516048 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C1705248 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0442111 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C1548799 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C1524073 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0449432 | lld:lifeskim |
| pubmed-article:11818163 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:11818163 | pubmed:issue | 9-10 | lld:pubmed |
| pubmed-article:11818163 | pubmed:dateCreated | 2002-1-30 | lld:pubmed |
| pubmed-article:11818163 | pubmed:abstractText | The efficacy of 10 pertussis vaccines prepared from various concentrations of pertussis toxin (PT) and filamentous hemagglutinin (FHA) was investigated in a murine model of respiratory infection (aerosol challenge model) and a murine intracerebral (ic) challenge model. PT was necessary as a vaccine component for protection against an ic challenge with Bordetella pertussis. FHA appeared to play an important role as a vaccine component in protection against an aerosol challenge with B. pertussis. Vaccines containing a small amount of FHA with a large amount of PT (FHA:PT=1:11 or 2:10, w/w) were strongly protective in both the aerosol challenge and the ic challenge models. Ratios of FHA:PT of 1:11 or 2:10 (w/w) might be suitable for future formulations. | lld:pubmed |
| pubmed-article:11818163 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11818163 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11818163 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11818163 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:11818163 | pubmed:issn | 0264-410X | lld:pubmed |
| pubmed-article:11818163 | pubmed:author | pubmed-author:SatoTakaakiT | lld:pubmed |
| pubmed-article:11818163 | pubmed:author | pubmed-author:WatanabeMineo... | lld:pubmed |
| pubmed-article:11818163 | pubmed:author | pubmed-author:KomatsuEijiE | lld:pubmed |
| pubmed-article:11818163 | pubmed:author | pubmed-author:AbeKatsuyoK | lld:pubmed |
| pubmed-article:11818163 | pubmed:author | pubmed-author:IyamaShigehar... | lld:pubmed |
| pubmed-article:11818163 | pubmed:author | pubmed-author:NagaiMasaakiM | lld:pubmed |
| pubmed-article:11818163 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11818163 | pubmed:day | 31 | lld:pubmed |
| pubmed-article:11818163 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:11818163 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11818163 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11818163 | pubmed:pagination | 1429-34 | lld:pubmed |
| pubmed-article:11818163 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11818163 | pubmed:meshHeading | pubmed-meshheading:11818163... | lld:pubmed |
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| pubmed-article:11818163 | pubmed:meshHeading | pubmed-meshheading:11818163... | lld:pubmed |
| pubmed-article:11818163 | pubmed:meshHeading | pubmed-meshheading:11818163... | lld:pubmed |
| pubmed-article:11818163 | pubmed:meshHeading | pubmed-meshheading:11818163... | lld:pubmed |
| pubmed-article:11818163 | pubmed:meshHeading | pubmed-meshheading:11818163... | lld:pubmed |
| pubmed-article:11818163 | pubmed:meshHeading | pubmed-meshheading:11818163... | lld:pubmed |
| pubmed-article:11818163 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:11818163 | pubmed:articleTitle | Efficacy of pertussis components in an acellular vaccine, as assessed in a murine model of respiratory infection and a murine intracerebral challenge model. | lld:pubmed |
| pubmed-article:11818163 | pubmed:affiliation | Research Center for Biologicals, The Kitasato Institute, 6-111 Arai, Kitamoto, 364-0026, Saitama, Japan. | lld:pubmed |
| pubmed-article:11818163 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11818163 | lld:pubmed |
