| pubmed-article:11807261 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C0014442 | lld:lifeskim |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C1418713 | lld:lifeskim |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C0010423 | lld:lifeskim |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C0427716 | lld:lifeskim |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C1304757 | lld:lifeskim |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C0851827 | lld:lifeskim |
| pubmed-article:11807261 | lifeskim:mentions | umls-concept:C1701901 | lld:lifeskim |
| pubmed-article:11807261 | pubmed:issue | Pt 2 | lld:pubmed |
| pubmed-article:11807261 | pubmed:dateCreated | 2002-1-24 | lld:pubmed |
| pubmed-article:11807261 | pubmed:abstractText | Phenylethanolamine N-methyltransferase, PNMT, utilizes the methylating cofactor S-adenosyl-L-methionine to catalyse the synthesis of adrenaline. Human PNMT has been crystallized in complex with an inhibitor and the cofactor product S-adenosyl-L-homocysteine using the hanging-drop technique with PEG 6000 and lithium chloride as precipitant. A critical requirement for crystallization was a high enzyme concentration (>90 mg ml(-1)) and cryocrystallography was used for high-quality data measurement. Diffraction data measured from a cryocooled crystal extend to a resolution of 2.3 A. Cryocooled crystals belong to space group P4(3)2(1)2 and have unit-cell parameters a = b = 94.3, c = 187.7 A. | lld:pubmed |
| pubmed-article:11807261 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11807261 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11807261 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11807261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11807261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11807261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11807261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11807261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11807261 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11807261 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:11807261 | pubmed:issn | 0907-4449 | lld:pubmed |
| pubmed-article:11807261 | pubmed:author | pubmed-author:BegunJakeJ | lld:pubmed |
| pubmed-article:11807261 | pubmed:author | pubmed-author:McLeishMichae... | lld:pubmed |
| pubmed-article:11807261 | pubmed:author | pubmed-author:CaineJoanne... | lld:pubmed |
| pubmed-article:11807261 | pubmed:author | pubmed-author:PalantElkaE | lld:pubmed |
| pubmed-article:11807261 | pubmed:author | pubmed-author:GrunewaldGary... | lld:pubmed |
| pubmed-article:11807261 | pubmed:author | pubmed-author:MartinJennife... | lld:pubmed |
| pubmed-article:11807261 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11807261 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:11807261 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11807261 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11807261 | pubmed:pagination | 314-5 | lld:pubmed |
| pubmed-article:11807261 | pubmed:dateRevised | 2007-7-24 | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:meshHeading | pubmed-meshheading:11807261... | lld:pubmed |
| pubmed-article:11807261 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:11807261 | pubmed:articleTitle | Crystallization of PNMT, the adrenaline-synthesizing enzyme, is critically dependent on a high protein concentration. | lld:pubmed |
| pubmed-article:11807261 | pubmed:affiliation | Centre for Drug Design and Development and Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane QLD 4072, Australia. | lld:pubmed |
| pubmed-article:11807261 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11807261 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11807261 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:5409 | entrezgene:pubmed | pubmed-article:11807261 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11807261 | lld:entrezgene |
