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pubmed-article:11751491pubmed:abstractTextThis study was designed to add new data about laryngeal carcinogenesis, a multistep process in which chemical and/or viral agents induce and promote successive alterations in growth factor-linked signal transmission pathways, genetic instability, and mutations in key genes involved in cell growth control. Epidemiological evidence suggests that human papillomavirus (HPV) infection may be associated with the development of laryngeal cancer.lld:pubmed
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pubmed-article:11751491pubmed:articleTitleHuman papillomavirus infection and epidermal growth factor receptor expression in primary laryngeal squamous cell carcinoma.lld:pubmed
pubmed-article:11751491pubmed:affiliationInstitute of Otolaryngology, Catholic University of the Sacred Heart, Largo A. Gemelli, 8, Rome 00168, Italy. iclot@rm.unicatt.itlld:pubmed
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