pubmed-article:11747698 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11747698 | lifeskim:mentions | umls-concept:C0001737 | lld:lifeskim |
pubmed-article:11747698 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
pubmed-article:11747698 | lifeskim:mentions | umls-concept:C1136211 | lld:lifeskim |
pubmed-article:11747698 | lifeskim:mentions | umls-concept:C1516670 | lld:lifeskim |
pubmed-article:11747698 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
pubmed-article:11747698 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:11747698 | pubmed:dateCreated | 2001-12-18 | lld:pubmed |
pubmed-article:11747698 | pubmed:abstractText | One hundred four serogroup A meningococci in our collection, isolated in Africa from 1988 to 1999, were characterized by multilocus sequence typing (MLST). Our results and data from the Internet indicate that sequence type 5 (ST-5) strains were responsible for most of African outbreaks and sporadic cases during this period. In 1995, a new clone, characterized by ST-7 sequence, emerged and was responsible for severe outbreaks in Chad (1998) and Sudan (1999). MLST and epidemiologic data indicate that ST-5 and ST-7 represent two virulent clones. These two STs, which belong to subgroup III, differ only in the pgm locus: allele pgm3 is characteristic for ST-5 and allele pgm19 for ST-7. Subgroup III strains were responsible for two pandemics in the 1960s and 1980s. Our data show that the third subgroup III pandemic has now reached Africa. | lld:pubmed |
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pubmed-article:11747698 | pubmed:language | eng | lld:pubmed |
pubmed-article:11747698 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11747698 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:11747698 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11747698 | pubmed:issn | 1080-6040 | lld:pubmed |
pubmed-article:11747698 | pubmed:author | pubmed-author:BlanchetGG | lld:pubmed |
pubmed-article:11747698 | pubmed:author | pubmed-author:CastelliPP | lld:pubmed |
pubmed-article:11747698 | pubmed:author | pubmed-author:NicolaiJJ | lld:pubmed |
pubmed-article:11747698 | pubmed:author | pubmed-author:RiglerTT | lld:pubmed |
pubmed-article:11747698 | pubmed:author | pubmed-author:StorRR | lld:pubmed |
pubmed-article:11747698 | pubmed:author | pubmed-author:DécoussetLL | lld:pubmed |
pubmed-article:11747698 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11747698 | pubmed:volume | 7 | lld:pubmed |
pubmed-article:11747698 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11747698 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11747698 | pubmed:pagination | 849-54 | lld:pubmed |
pubmed-article:11747698 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:11747698 | pubmed:articleTitle | Clonal expansion of sequence type (ST-)5 and emergence of ST-7 in serogroup A meningococci, Africa. | lld:pubmed |
pubmed-article:11747698 | pubmed:affiliation | Institut de Médecine Tropicale du Service de Santé des Armées, World Organization Collaborating Center, Marseille Armées, France. imtssa.meningo.free.fr | lld:pubmed |
pubmed-article:11747698 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:11747698 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:11747698 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
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