| pubmed-article:11710021 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11710021 | lifeskim:mentions | umls-concept:C0032712 | lld:lifeskim |
| pubmed-article:11710021 | lifeskim:mentions | umls-concept:C0036576 | lld:lifeskim |
| pubmed-article:11710021 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:11710021 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:11710021 | pubmed:dateCreated | 2001-11-16 | lld:pubmed |
| pubmed-article:11710021 | pubmed:abstractText | A new macromolecular catalyst, which is composed of nonnatural ribonucleotide, was synthesized by the in vitro selection (SELEX) method. A pool of RNAs consisting of random sequences was obtained by transcription from a pool of synthetic random-sequence DNAs in the presence of 2'-aminocytidine triphosphate (2'-amino-CTP) instead of CTP. The pool was incubated with N-methylmesoporphyrin-immobilized gel; bound nonnatural RNAs were then collected and amplified by reverse-transcription following the polymerase chain reaction. The amplified DNAs were again transcribed in the presence of 2'-amino-CTP and applied to the gel. This selection process was repeated 10 times. The selected RNAs were cloned and sequenced. The RNAs not only bound to the ligand, N-methylmesoporphyrin but also catalyzed the metalation reaction of porphyrin. | lld:pubmed |
| pubmed-article:11710021 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11710021 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11710021 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11710021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11710021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11710021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11710021 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11710021 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11710021 | pubmed:issn | 1525-7797 | lld:pubmed |
| pubmed-article:11710021 | pubmed:author | pubmed-author:ItoYY | lld:pubmed |
| pubmed-article:11710021 | pubmed:author | pubmed-author:ImanishiYY | lld:pubmed |
| pubmed-article:11710021 | pubmed:author | pubmed-author:KawazoeNN | lld:pubmed |
| pubmed-article:11710021 | pubmed:author | pubmed-author:TeramotoNN | lld:pubmed |
| pubmed-article:11710021 | pubmed:author | pubmed-author:IchinariHH | lld:pubmed |
| pubmed-article:11710021 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11710021 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:11710021 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11710021 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11710021 | pubmed:pagination | 681-6 | lld:pubmed |
| pubmed-article:11710021 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:meshHeading | pubmed-meshheading:11710021... | lld:pubmed |
| pubmed-article:11710021 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11710021 | pubmed:articleTitle | In vitro selection of nonnatural ribozyme-catalyzing porphyrin metalation. | lld:pubmed |
| pubmed-article:11710021 | pubmed:affiliation | Department of Biological Science and Technology, Faculty of Engineering, University of Tokushima, Tokushima 770-8506, Japan. | lld:pubmed |
| pubmed-article:11710021 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11710021 | pubmed:publicationType | In Vitro | lld:pubmed |
