| pubmed-article:11707360 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0175430 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0006685 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:11707360 | lifeskim:mentions | umls-concept:C1707723 | lld:lifeskim |
| pubmed-article:11707360 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:11707360 | pubmed:dateCreated | 2001-11-14 | lld:pubmed |
| pubmed-article:11707360 | pubmed:abstractText | We used whole cell voltage clamp recordings from neurones in rat auditory brainstem slices to study the Ca(2+) channel types involved in triggering synaptic glutamate and glycine release in the medial superior olivary nucleus. Glutamate release from the anterior ventral cochlear (aVCN) bushy neurone synapse did not involve L-type Ca(2+) channels (alpha(1C-D); Ca(V)1.2-1.3), but was mediated with similar efficacies by both N-type (alpha(1B); Ca(V)2.2) and the P/Q-type Ca(2+) channels (alpha(1A); Ca(V)2.1). Glycine release from the medial nucleus of the trapezoid body (MNTB) synapse was mediated predominantly by P/Q-type Ca(2+) channels, but with a significant contribution from N-type Ca(2+) channels. Combined application of the P/Q- and N-type Ca(2+) channel toxins, omega-agatoxin IVA and omega-conotoxin GVIA, left a very small remnant of both the inhibitory and excitatory postsynaptic currents, probably reflecting a minimal contribution of R-type Ca(2+) channels (alpha(1E); Ca(V)2.3) to transmitter release. In contrast with aVCN bushy neurones, MNTB somata lacked both T- (alpha(1G-I); Ca(V)3.1-3.3) and L-type channels, but expressed a higher proportion of P/Q-type Ca(2+) channels. | lld:pubmed |
| pubmed-article:11707360 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11707360 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11707360 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11707360 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11707360 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11707360 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11707360 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:11707360 | pubmed:issn | 0378-5955 | lld:pubmed |
| pubmed-article:11707360 | pubmed:author | pubmed-author:OwensSS | lld:pubmed |
| pubmed-article:11707360 | pubmed:author | pubmed-author:ForsytheI DID | lld:pubmed |
| pubmed-article:11707360 | pubmed:author | pubmed-author:Barnes-Davies... | lld:pubmed |
| pubmed-article:11707360 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11707360 | pubmed:volume | 162 | lld:pubmed |
| pubmed-article:11707360 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11707360 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11707360 | pubmed:pagination | 134-45 | lld:pubmed |
| pubmed-article:11707360 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:meshHeading | pubmed-meshheading:11707360... | lld:pubmed |
| pubmed-article:11707360 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11707360 | pubmed:articleTitle | Calcium channels triggering transmitter release in the rat medial superior olive. | lld:pubmed |
| pubmed-article:11707360 | pubmed:affiliation | Ion Channel Group, Department of Cell Physiology and Pharmacology, University of Leicester, P.O. Box 138, LE1 9HN, Leicester, UK. mb27@leicester.ac.uk | lld:pubmed |
| pubmed-article:11707360 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11707360 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:11707360 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:11707360 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11707360 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11707360 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11707360 | lld:pubmed |
