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pubmed-article:11704324pubmed:abstractTextThe majority of clinical trials have shown that high-grade prostate cancer patients treated with androgen deprivation (AD) plus radiation (RT) have a survival advantage over those treated with RT alone. One possible mechanism for such a favorable interaction is that AD sensitizes cells to radiation. Animal model studies have provided suggestive evidence that AD sensitizes cells to radiation, but this mechanism is difficult to confirm conclusively in vivo. This question was investigated in LNCaP cells grown in vitro.lld:pubmed
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pubmed-article:11704324pubmed:articleTitleLack of prostate cancer radiosensitization by androgen deprivation.lld:pubmed
pubmed-article:11704324pubmed:affiliationDepartment of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. a_pollack@fccc.edulld:pubmed
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