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pubmed-article:11677420pubmed:abstractTextSarcoidosis is a chronic systemic disease, characterized by an imbalance of immunity processes and the presence of granuloma. Endothelin-1, a new vasoactive and bronchoconstrictive peptide, is a powerful mitogen for smooth muscle cells and fibroblasts and plays a role in the inflammation state. We postulate that endothelin-1 has a role in sarcoidosis.lld:pubmed
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pubmed-article:11677420pubmed:articleTitlePlasma levels of endothelin-1 increase in patients with sarcoidosis and fall after disease remission.lld:pubmed
pubmed-article:11677420pubmed:affiliationDepartment of Clinical Science, Chair of Internal Medicine, University La Sapienza, Rome, Italy. claudio.letizia@uniromal.itlld:pubmed
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