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pubmed-article:11672622pubmed:abstractTextComparative functional neuroimaging studies using the block design paradigm have previously demonstrated that there are no significant differences in the location of areas of cerebral activation when native Chinese speakers independently process single words or sentences in both the Chinese (first) and English (second) languages. While it has also been documented that significant domains of brain response include the inferior to middle left frontal lobe, the latency, amplitude and duration of the associated hemodynamic changes during isolated neural processing of Chinese and English languages still remain unknown. The aim of this study, therefore, was to examine the characteristics of the hemodynamic alterations in the above-mentioned regions with event-related functional MRI (ER-fMRI) when native Chinese speakers performed verb generation tasks in both the Chinese (first) and English (second) languages. Our results demonstrate the presence of a similar neural activity-induced hemodynamic response in the inferior to middle left frontal lobe during both tasks. Further, there were also no statistically significant differences among the variables that described the hemodynamic response curves. These findings strongly imply that the underlying neural mechanism for Chinese (first) and English (second) language processing may be similar in native Chinese speakers.lld:pubmed
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pubmed-article:11672622pubmed:authorpubmed-author:LinH UHUlld:pubmed
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pubmed-article:11672622pubmed:authorpubmed-author:FengC MCMlld:pubmed
pubmed-article:11672622pubmed:authorpubmed-author:MahankaliSSlld:pubmed
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pubmed-article:11672622pubmed:pagination643-7lld:pubmed
pubmed-article:11672622pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:11672622pubmed:articleTitleCerebral hemodynamic response in Chinese (first) and English (second) language processing revealed by event-related functional MRI.lld:pubmed
pubmed-article:11672622pubmed:affiliationResearch Imaging Center, University of Texas Health Science Center, San Antonio, TX, USA.lld:pubmed
pubmed-article:11672622pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11672622pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:11672622pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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