| pubmed-article:11597390 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0021400 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C1522424 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0039195 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0887910 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0041361 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C1705822 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:11597390 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:11597390 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:11597390 | pubmed:dateCreated | 2001-10-12 | lld:pubmed |
| pubmed-article:11597390 | pubmed:abstractText | We investigated influenza virosomes as a TAA-gene delivery system for use in TAA-directed anti-cancer vaccine therapy. An engineered plasmid (GC90) expressing the parathyroid hormone-related peptide (PTH-rP), a protein secreted by prostate and lung carcinoma cells, was included in influenza virosomes (GC90V). The ability of GC90V to elicit a PTH-rP-specific cytotoxic T cell (CTL) response was demonstrated in BALB/c mice immunised with intranasal (i.n.) GC90V+/-adjuvant subcutaneous (s.c.) interleukin-2 (IL-2). A PTH-rP-specific CTL response with antitumour activity was also demonstrated in human peripheral blood mononuclear cells (PBMC) stimulated in vitro with GC90V infected autologous dendritic cells (DC). These results provide a rationale for investigating GC90V in clinical trials of anticancer vaccine therapy. | lld:pubmed |
| pubmed-article:11597390 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11597390 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11597390 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11597390 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:11597390 | pubmed:issn | 0959-8049 | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:ValensinP EPE | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:FranciniGG | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:MichellII | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:GiorgiGG | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:GluckRR | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:SabatinoMM | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:CorrealePP | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:CusiM GMG | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:PetrioliRR | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:ZurbriggenRR | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:NenciniCC | lld:pubmed |
| pubmed-article:11597390 | pubmed:author | pubmed-author:PozzessereDD | lld:pubmed |
| pubmed-article:11597390 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11597390 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:11597390 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11597390 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11597390 | pubmed:pagination | 2097-103 | lld:pubmed |
| pubmed-article:11597390 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:11597390 | pubmed:meshHeading | pubmed-meshheading:11597390... | lld:pubmed |
| pubmed-article:11597390 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11597390 | pubmed:articleTitle | Tumour-associated antigen (TAA)-specific cytotoxic T cell (CTL) response in vitro and in a mouse model, induced by TAA-plasmids delivered by influenza virosomes. | lld:pubmed |
| pubmed-article:11597390 | pubmed:affiliation | Medical Oncology Division, Medicine School, Siena University, 53100, Siena, Italy. | lld:pubmed |
| pubmed-article:11597390 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11597390 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11597390 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11597390 | lld:pubmed |
