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pubmed-article:11591607pubmed:abstractTextDaily rhythms of mammalian physiology and endocrinology are regulated by circadian pacemakers. The master circadian pacemaker resides in the suprachiasmatic nucleus, which is located in the hypothalamus of the brain, but circadian oscillators also exist in peripheral tissues. Because many studies have demonstrated apparent circadian variations in the frequency of cardiovascular disorders, it is of great interest to investigate a possible relation between circadian gene expression and cardiovascular function. We examined whether a circadian oscillation system exists in the aorta and/or in cultured vascular smooth muscle cells (VSMCs).lld:pubmed
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pubmed-article:11591607pubmed:articleTitleAngiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells.lld:pubmed
pubmed-article:11591607pubmed:affiliationDivision of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.lld:pubmed
pubmed-article:11591607pubmed:publicationTypeJournal Articlelld:pubmed
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