pubmed-article:11578842 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0013935 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0033487 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0108303 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C1515877 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C0439799 | lld:lifeskim |
pubmed-article:11578842 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
pubmed-article:11578842 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:11578842 | pubmed:dateCreated | 2001-10-1 | lld:pubmed |
pubmed-article:11578842 | pubmed:abstractText | Propofol (2,6-diisopropylphenol) is an intravenous anesthetic agent structurally unrelated to any other intravenous anesthetics. We examined the effect of propofol on a rat vanilloid receptor that was expressed in the human embryonic kidney (HEK) 293 cells by using calcium imaging method. Propofol caused a concentration-dependent increase in [Ca(2+)](i) in the HEK293 cells with the receptor. These responses were inhibited by removing extracellular calcium ions. The propofol-evoked increase in [Ca(2+)](i) in the HEK293 cells with the receptor was partially inhibited by capsazepine, a competitive antagonist of capsaicin. We conclude that propofol acts as an agonist for the receptor. | lld:pubmed |
pubmed-article:11578842 | pubmed:language | eng | lld:pubmed |
pubmed-article:11578842 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11578842 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11578842 | pubmed:month | Oct | lld:pubmed |
pubmed-article:11578842 | pubmed:issn | 0304-3940 | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:KohamaKK | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:SudoMM | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:TomiokaAA | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:NakamuraAA | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:TsutsumiSS | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:TakagishiKK | lld:pubmed |
pubmed-article:11578842 | pubmed:author | pubmed-author:ShirakuraKK | lld:pubmed |
pubmed-article:11578842 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11578842 | pubmed:day | 12 | lld:pubmed |
pubmed-article:11578842 | pubmed:volume | 312 | lld:pubmed |
pubmed-article:11578842 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11578842 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11578842 | pubmed:pagination | 45-9 | lld:pubmed |
pubmed-article:11578842 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
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pubmed-article:11578842 | pubmed:meshHeading | pubmed-meshheading:11578842... | lld:pubmed |
pubmed-article:11578842 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11578842 | pubmed:articleTitle | Propofol activates vanilloid receptor channels expressed in human embryonic kidney 293 cells. | lld:pubmed |
pubmed-article:11578842 | pubmed:affiliation | Department of Pharmacology, Gunma University School of Medicine, Maebashi, Gunma 371-8511, Japan. stutumi@med.gunma-u.ac.jp | lld:pubmed |
pubmed-article:11578842 | pubmed:publicationType | Journal Article | lld:pubmed |
entrez-gene:83810 | entrezgene:pubmed | pubmed-article:11578842 | lld:entrezgene |
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