| pubmed-article:11570360 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11570360 | lifeskim:mentions | umls-concept:C0225326 | lld:lifeskim |
| pubmed-article:11570360 | lifeskim:mentions | umls-concept:C1304649 | lld:lifeskim |
| pubmed-article:11570360 | lifeskim:mentions | umls-concept:C0004048 | lld:lifeskim |
| pubmed-article:11570360 | lifeskim:mentions | umls-concept:C1444754 | lld:lifeskim |
| pubmed-article:11570360 | lifeskim:mentions | umls-concept:C0596244 | lld:lifeskim |
| pubmed-article:11570360 | lifeskim:mentions | umls-concept:C0086930 | lld:lifeskim |
| pubmed-article:11570360 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:11570360 | pubmed:dateCreated | 2001-9-24 | lld:pubmed |
| pubmed-article:11570360 | pubmed:abstractText | We briefly review the evidence that the carcinogenic risk posed by inhaled fibers depends principally on the lung burden of long fibers. We use a deposition clearance model to generate time-dependent lung burdens in rats of a dozen long fibers for various exposure concentrations. Together with a previously estimated potency factor for long fibers, we use the generated lung burdens to estimate risks of lung cancer associated with inhaled fibers in rats. Over a broad range of exposure concentrations, excess risk is a linear function of exposure concentration. Excess risk of lung cancer is also a linear function of weighted half-life for fibers for which the weighted half-life is short compared to the life span of the rat. We propose an approach to estimating human lung cancer risk associated with inhaled fibers from animal studies. | lld:pubmed |
| pubmed-article:11570360 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11570360 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11570360 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11570360 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11570360 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11570360 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11570360 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:11570360 | pubmed:issn | 0895-8378 | lld:pubmed |
| pubmed-article:11570360 | pubmed:author | pubmed-author:BrownR CRC | lld:pubmed |
| pubmed-article:11570360 | pubmed:author | pubmed-author:MoolgavkarS... | lld:pubmed |
| pubmed-article:11570360 | pubmed:author | pubmed-author:TurimJJ | lld:pubmed |
| pubmed-article:11570360 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11570360 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:11570360 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11570360 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11570360 | pubmed:pagination | 755-72 | lld:pubmed |
| pubmed-article:11570360 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:meshHeading | pubmed-meshheading:11570360... | lld:pubmed |
| pubmed-article:11570360 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11570360 | pubmed:articleTitle | Biopersistence, fiber length, and cancer risk assessment for inhaled fibers. | lld:pubmed |
| pubmed-article:11570360 | pubmed:affiliation | Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. smoolgav@fhcrc.org | lld:pubmed |
| pubmed-article:11570360 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11570360 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11570360 | lld:pubmed |
