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pubmed-article:11562666pubmed:abstractTextThe optimal sentinel lymph node (SLN) biopsy technique remains undefined in breast cancer. Injecting radiotracer or blue dye by a variety of routes seems to stage the axilla with comparable accuracy, and we have hypothesized that the dermal and the parenchymal lymphatics of the breast drain to the same SLN in most patients. Two previous studies from our institution support this concept: (1) a single-surgeon series of 200 consecutive SLN biopsy procedures demonstrating a high dye-isotope concordance for both intradermal (ID) and intraparenchymal (IP) isotope injection, and (2) a series of 100 procedures validated by a backup axillary dissection (ALND) in which the false-negative rate following ID isotope injection was comparable to that of our previous results with IP injection. Here, we directly compare the results of SLN biopsy using either ID or IP isotope injection for our entire experience of SLN biopsy procedures in which a backup ALND was done.lld:pubmed
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pubmed-article:11562666pubmed:authorpubmed-author:MartinR CRClld:pubmed
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pubmed-article:11562666pubmed:pagination432-8lld:pubmed
pubmed-article:11562666pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:11562666pubmed:year2001lld:pubmed
pubmed-article:11562666pubmed:articleTitleIntradermal isotope injection is superior to intramammary in sentinel node biopsy for breast cancer.lld:pubmed
pubmed-article:11562666pubmed:affiliationBreast Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.lld:pubmed
pubmed-article:11562666pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:11562666pubmed:publicationTypeComparative Studylld:pubmed
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