| pubmed-article:11533309 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11533309 | lifeskim:mentions | umls-concept:C0006826 | lld:lifeskim |
| pubmed-article:11533309 | lifeskim:mentions | umls-concept:C0017797 | lld:lifeskim |
| pubmed-article:11533309 | pubmed:issue | 9 Suppl | lld:pubmed |
| pubmed-article:11533309 | pubmed:dateCreated | 2001-9-4 | lld:pubmed |
| pubmed-article:11533309 | pubmed:abstractText | Glutamine is the most abundant free amino acid in the human body; it is essential for the growth of normal and neoplastic cells and for the culture of many cell types. Cancer has been described as a nitrogen trap. The presence of a tumor produces great changes in host glutamine metabolism in such a way that host nitrogen metabolism is accommodated to the tumor-enhanced requirements of glutamine. To be used, glutamine must be transported into tumor mitochondria. Thus, an overview of the role of glutamine in cancer requires not only a discussion of host and tumor glutamine metabolism, but also its circulation and transport. Because glutamine depletion has adverse effects for the host, the effect of glutamine supplementation in the tumor-bearing state should also be studied. This communication reviews the state of knowledge of glutamine and cancer, including potential therapeutic implications. | lld:pubmed |
| pubmed-article:11533309 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11533309 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11533309 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11533309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11533309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:11533309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11533309 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11533309 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:11533309 | pubmed:issn | 0022-3166 | lld:pubmed |
| pubmed-article:11533309 | pubmed:author | pubmed-author:MedinaM AMA | lld:pubmed |
| pubmed-article:11533309 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11533309 | pubmed:volume | 131 | lld:pubmed |
| pubmed-article:11533309 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11533309 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11533309 | pubmed:pagination | 2539S-42S; discussion 2550S-1S | lld:pubmed |
| pubmed-article:11533309 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:11533309 | pubmed:meshHeading | pubmed-meshheading:11533309... | lld:pubmed |
| pubmed-article:11533309 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11533309 | pubmed:articleTitle | Glutamine and cancer. | lld:pubmed |
| pubmed-article:11533309 | pubmed:affiliation | Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Málaga, Málaga, Spain. | lld:pubmed |
| pubmed-article:11533309 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11533309 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:11533309 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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