| pubmed-article:11526151 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11526151 | lifeskim:mentions | umls-concept:C0019169 | lld:lifeskim |
| pubmed-article:11526151 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:11526151 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:11526151 | lifeskim:mentions | umls-concept:C0439659 | lld:lifeskim |
| pubmed-article:11526151 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:11526151 | pubmed:dateCreated | 2001-8-29 | lld:pubmed |
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| pubmed-article:11526151 | pubmed:abstractText | Mutations that prevent the expression of the hepatitis B e antigen frequently emerge in the immunoreactive phase of infection. The predominant mutation, the precore G-->A-1896 mutation, is restricted by the variability at position 1858 and is rare in strains with cytosine at nucleotide 1858. The C-1858 variant is characteristic of genotype A. It also occurs in genotypes C and F, but not in B, D, or E, explaining the geographical variation in the prevalence of precore mutants. C-1858 strains have been frequently observed in southeast Asia, but have not been phylogenetically characterized. By sequencing eight complete hepatitis B virus genomes, C-1858 variants of east Asian origin were found to constitute a phylogenetic entity within genotype C that probably diverged several hundred years ago. Further study of the distribution of this variant is warranted. | lld:pubmed |
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| pubmed-article:11526151 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11526151 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11526151 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11526151 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11526151 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:11526151 | pubmed:issn | 0095-1137 | lld:pubmed |
| pubmed-article:11526151 | pubmed:author | pubmed-author:HannounCC | lld:pubmed |
| pubmed-article:11526151 | pubmed:author | pubmed-author:LindhMM | lld:pubmed |
| pubmed-article:11526151 | pubmed:author | pubmed-author:HorakSS | lld:pubmed |
| pubmed-article:11526151 | pubmed:author | pubmed-author:AlestigEE | lld:pubmed |
| pubmed-article:11526151 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11526151 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:11526151 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11526151 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11526151 | pubmed:pagination | 3200-3 | lld:pubmed |
| pubmed-article:11526151 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:11526151 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11526151 | pubmed:articleTitle | Phylogenetic origin of hepatitis B virus strains with precore C-1858 variant. | lld:pubmed |
| pubmed-article:11526151 | pubmed:affiliation | Department of Clinical Virology, Göteborg University, Göteborg, Sweden. | lld:pubmed |
| pubmed-article:11526151 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11526151 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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