pubmed-article:11520766 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0013018 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0225336 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0010031 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0029205 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0007620 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0030899 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0596138 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
pubmed-article:11520766 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
pubmed-article:11520766 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:11520766 | pubmed:dateCreated | 2001-8-24 | lld:pubmed |
pubmed-article:11520766 | pubmed:abstractText | Scientific interest in pentoxifylline has been reawakened owing to the recognised effects of this drug on immune functions, particularly its influence on cytokine production. In a previous study, the authors demonstrated that spiking of organ culture media with endotoxin elicited a marked enhancement in the release of IL-6 and IL-8 from corneal tissue and that these events coincided with degenerative changes in endothelial cells and a higher incidence of actual loss among this population. Since traces of donor derived endotoxin can be detected in up to 50% of corneal organ cultures, this substance may have a direct influence on graft viability or trigger inflammatory responses in the host. They, therefore, wished to ascertain whether supplementation of media with pentoxifylline improved endothelial cell survival in organ cultured donor corneas. | lld:pubmed |
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pubmed-article:11520766 | pubmed:language | eng | lld:pubmed |
pubmed-article:11520766 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:11520766 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:11520766 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:11520766 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:11520766 | pubmed:month | Sep | lld:pubmed |
pubmed-article:11520766 | pubmed:issn | 0007-1161 | lld:pubmed |
pubmed-article:11520766 | pubmed:author | pubmed-author:BöhnkeMM | lld:pubmed |
pubmed-article:11520766 | pubmed:author | pubmed-author:VenturaA CAC | lld:pubmed |
pubmed-article:11520766 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:11520766 | pubmed:volume | 85 | lld:pubmed |
pubmed-article:11520766 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:11520766 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:11520766 | pubmed:pagination | 1110-4 | lld:pubmed |
pubmed-article:11520766 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:11520766 | pubmed:year | 2001 | lld:pubmed |
pubmed-article:11520766 | pubmed:articleTitle | Pentoxifylline influences the autocrine function of organ cultured donor corneas and enhances endothelial cell survival. | lld:pubmed |
pubmed-article:11520766 | pubmed:affiliation | Augen- und Poliklinik des Inselspitals, Universität Bern, CH-3010 Bern, Switzerland. draventura@oftalmo.epm.com.br | lld:pubmed |
pubmed-article:11520766 | pubmed:publicationType | Journal Article | lld:pubmed |