pubmed-article:1146503 | pubmed:abstractText | 46XY, normal male karyotype (G-banded) was noted in each patient with progressive external ophthalmoplegia. Although vacuoles have been recognized in other conditions, their presence in significant numbers in the diseases under scrutiny suggests the possibility of a common offending agent. It is likely that vacuolation is a pathological indication of infection by slow viruses. | lld:pubmed |